STAM Antibody

Catalog Number:

36172

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q92783
NCBI Gene ID: 8027
Gene Accssion: BC030586

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STAM protein.

Applications:

IHC

Background:

This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF