APLF Antibody

Catalog Number:

36118

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IW19
NCBI Gene ID: 200558
Gene Accssion: BC041144

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human aprataxin and PNKP like factor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total APLF protein.

Applications:

IHC

Background:

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF