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ATG5 Antibody

Catalog Number:

36116
other_names: ASP; APG5; APG5L; hAPG5; APG5-LIKE

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H1Y0
NCBI Gene ID: 9474
Gene Accssion: BC002699

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATG5 protein.

Applications:

WB IHC

Background:

Autophagy protein 5?is a?protein?that in humans is encoded by the?ATG5?gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

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