ANAPC10 Antibody

Catalog Number:

36112

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UM13
NCBI Gene ID: 10393
Gene Accssion: BC005217

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ANAPC10 protein.

Applications:

IHC

Background:

ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940)

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF