CFL1 Antibody

Catalog Number:

36360

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P23528
NCBI Gene ID: 1072
Gene Accssion: BC011005

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CFL1 protein.

Applications:

WB

Background:

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF