ACMSD Antibody

Catalog Number:

36019

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8TDX5
NCBI Gene ID: 130013
Gene Accssion: BC016018

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACMSD protein.

Applications:

WB

Background:

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF