ATPIF1 Antibody

Catalog Number:

35986

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UII2
NCBI Gene ID: 93974
Gene Accssion: BC009677

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human ATPase inhibitory factor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATPIF1 protein.

Applications:

WB IHC

Background:

ATPase inhibitor, mitochondrial?is an?enzyme?that in humans is encoded by the?ATPIF1?gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase, possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states, dimer (the active state) and tetramer.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF