MAPT Antibody

Catalog Number:

35947

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P10636
NCBI Gene ID: 4137
Gene Accssion: BC114948

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human microtubule-associated protein tau

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAPT protein.

Applications:

WB

Background:

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF