PRMT2 Antibody

Catalog Number:

35888

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P55345
NCBI Gene ID: 3275
Gene Accssion: BC000727

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human protein arginine methyltransferase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PRMT2 protein.

Applications:

IHC

Background:

Protein arginine N-methyltransferase 2?is an?enzyme?that in humans is encoded by the?PRMT2?gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF