RAMP3 Antibody

Catalog Number:

35886

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60896
NCBI Gene ID: 10268
Gene Accssion: BC022304

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human receptor (G protein-coupled) activity modifying protein 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RAMP3 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF