PIK3R1 Antibody

Catalog Number:

35878

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P27986
NCBI Gene ID: 5295
Gene Accssion: BC030815

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3R1 protein.

Applications:

IHC

Background:

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF