OPCML Antibody

Catalog Number:

35854

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14982
NCBI Gene ID: 4978
Gene Accssion: BC117254

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human opioid binding protein/cell adhesion molecule-like

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OPCML protein.

Applications:

WB

Background:

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF