MYLK2 Antibody

Catalog Number:

35816

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H1R3
NCBI Gene ID: 85366
Gene Accssion: BC069627

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human myosin light chain kinase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYLK2 protein.

Applications:

WB

Background:

This gene encodes a?myosin light chain kinase, a?calcium?/?calmodulin?dependent enzyme, that is exclusively expressed in adult skeletal muscle. The MYLK2 gene expresses skMLCK more prevalently in fast twitch muscle fibers as compared to slow twitch muscle fibers. Calmodulin is composed of two terminal domains (N,C) each containing two E-F hand motifs that bind to Ca2+. Upon saturation of Ca2+, Calmodulin undergoes a conformation change allowing it to bind with a target protein such as skMLCK.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF