MFN1 Antibody

Catalog Number:

35813

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IWA4
NCBI Gene ID: 55669
Gene Accssion: BC040557

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human mitofusin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MFN1 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF