IRAK4 Antibody

Catalog Number:

35788

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NWZ3
NCBI Gene ID: 51135
Gene Accssion: BC013316

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human interleukin-1 receptor-associated kinase 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IRAK4 protein.

Applications:

IHC

Background:

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF