HSPB8 Antibody

Catalog Number:

35772

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UJY1
NCBI Gene ID: 26353
Gene Accssion: BC002673

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HSPB8 protein.

Applications:

IHC

Background:

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF