FASTK Antibody

Catalog Number:

35737

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14296
NCBI Gene ID: 10922
Gene Accssion: BC000377

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human fas-activated serine/threonine kinase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FASTK protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF