APOA5 Antibody

Catalog Number:

34429

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q6Q788
NCBI Gene ID: 116519

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human APOA5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total APOA5 protein.

Applications:

WB

Background:

Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) By similarity. Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.

van Der Vliet H.N., J. Biol. Chem. 276:44512-44520(2001) [PubMed: 11577099].
Beckstead J.A., Biochemistry 42:9416-9423(2003) [PubMed: 12899628].
Fullerton S.M., Hum. Genet. 115:36-56(2004) [PubMed: 15108119].

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF