AMOTL1 Antibody

Catalog Number:

34421

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8IY63
NCBI Gene ID: 154810

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human AMOTL1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AMOTL1 protein.

Applications:

IHC

Background:

Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.

Bratt A., Gene 298:69-77(2002).
Bratt A., Gene 310:231-231(2003).
Yu L.-R., J. Proteome Res. 6:4150-4162(2007).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF