DISC1 Antibody

Catalog Number:

31185

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P48664
Gene ID:6511

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 737-750 amino acids of Human disrupted in schizophrenia 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total DISC1 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Predicted MW: 60kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF