PIDD Polyclonal Antibody

Catalog Number:

30614

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9HB75
NCBI Gene ID:55367

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human PIDD (NP_665893.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:100

Datasheet PDF