Product Datasheet
CYP24A1 Polyclonal Antibody
Catalog Number: 30275
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q07973
NCBI Gene ID:1591
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CYP24A1 (NP_001122387.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- IHC 1:50 - 1:100
IF 1:50 - 1:100
- other_names:
- CYP24A1; CP24; CYP24; HCAI; HCINF1; P450-CC24; cytochrome P450 family 24 subfamily A member 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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