Product Datasheet  
BAK1 Polyclonal Antibody  
Catalog Number: 30248  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q16611
    NCBI Gene ID:578
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • A synthetic peptide of human BAK1
  • reactivity：  
  • Human,Rat
  • appl_detail：  
  • WB 1:500 - 1:2000
    IHC 1:50 - 1:100
  • other_names：  
  • BAK1; BAK; BAK-LIKE; BCL2L7; CDN1; BCL2 antagonist/killer 1
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IHC
  • Background：  
  • The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.



 
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