Product Datasheet
FKBP1B Polyclonal Antibody
Catalog Number: 29825
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P68106
NCBI Gene ID:2281
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human FKBP1B (NP_473374.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
- other_names:
- FKBP1B; FKBP12.6; FKBP1L; OTK4; PKBP1L; PPIase; FK506 binding protein 1B
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
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