Product Datasheet
THEM4 Polyclonal Antibody
Catalog Number: 29505
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5T1C6
NCBI Gene ID:117145
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human THEM4 (NP_444283.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- THEM4; CTMP; thioesterase superfamily member 4
- Purification:
- Affinity purification
- Background:
- Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.
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