Product Datasheet  
SMPD4 Polyclonal Antibody  
Catalog Number: 28986  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9NXE4
    NCBI Gene ID:55627
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human SMPD4 (NP_060421.2).
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:200 - 1:2000
  • other_names：  
  • SMPD4; NET13; NSMASE-3; NSMASE3; sphingomyelin phosphodiesterase 4
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.



 
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