Product Datasheet
IVD Polyclonal Antibody
Catalog Number: 28898
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P26440
NCBI Gene ID:3712
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human IVD (NP_002216.2).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:200 - 1:2000
IHC 1:50 - 1:200
- other_names:
- IVD; ACAD2; isovaleryl-CoA dehydrogenase
- Purification:
- Affinity purification
- Background:
- Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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