Product Datasheet
GUCY1B3 Polyclonal Antibody
Catalog Number: 28897
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q02153
NCBI Gene ID:2983
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GUCY1B3 (NP_000848.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:200 - 1:2000
IHC 1:50 - 1:200
- other_names:
- GUCY1B3; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1; guanylate cyclase soluble subunit beta-1
- Purification:
- Affinity purification
- Background:
- This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
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