Product Datasheet
OSBPL2 Polyclonal Antibody
Catalog Number: 28455
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9H1P3
NCBI Gene ID:9885
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human OSBPL2 (NP_653081.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- OSBPL2; DFNA67; DNFA67; ORP-2; ORP2; oxysterol binding protein like 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
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