Product Datasheet
GUCY2C Polyclonal Antibody
Catalog Number: 27477
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P25092
NCBI Gene ID:2984
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GUCY2C (NP_004954.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- GUCY2C; DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR; guanylate cyclase 2C
- Purification:
- Affinity purification
- Background:
- This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
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