Product Datasheet
VPS24 Polyclonal Antibody
Catalog Number: 27363
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y3E7
NCBI Gene ID:51652
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human VPS24 (NP_057163.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- CHMP3; CGI-149; NEDF; VPS24; charged multivesicular body protein 3
- Purification:
- Affinity purification
- Background:
- This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.
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