Product Datasheet
DAG1 Polyclonal Antibody
Catalog Number: 27283
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q14118
NCBI Gene ID:1605
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DAG1 (NP_004384.4).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:1000
IF 1:20 - 1:100
- other_names:
- DAG1; 156DAG; A3a; AGRNR; DAG; MDDGA9; MDDGC7; MDDGC9; dystroglycan
- Purification:
- Affinity purification
- Background:
- This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
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