Product Datasheet
MARCO Polyclonal Antibody
Catalog Number: 27273
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UEW3
NCBI Gene ID:8685
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MARCO (NP_006761.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:1000
- other_names:
- MARCO; SCARA2; SR-A6; macrophage receptor MARCO
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
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