Product Datasheet  
SIGLEC15 Antibody  
Catalog Number: 25434  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q6ZMC9
    Gene ID:284266
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 15 amino acid peptide near the amino terminus of human SIGLEC15.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Sialic acid-binding Ig-like lectin 15, Siglec-15, CD33L3, CD33 antigen-like 3, HST1361
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.



 
© Signalway Biotechnology All Rights Reserved.