Product Datasheet  
NKX2-2 Antibody  
Catalog Number: 25430  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O95096
    Gene ID:4821
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 19 amino acid peptide near the center of human NKX2-2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • NK2 homeobox 2, NKX2B
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • NKX2-2 antibody is predicted to not cross-react with other NK2 homeobox family members.
  • Applications：  
  • ELISA WB
  • Background：  
  • NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α-, β- and PP cells , and in NKX2-2-null mice embryos, all β-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.



 
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