Product Datasheet
SPINK2 Antibody
Catalog Number: 25415
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8BMY7
Gene ID:69982
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 16 amino acid peptide near the carboxy terminus of human SPINK2.
- other_names:
- Serine peptidase inhibitor kazal type 2, acrosin-trypsin inhibitor
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- SPINK2 antibody is predicted to not cross-react with other SPINK family members.
- Background:
- Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.
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