Product Datasheet
MS4A6A Antibody
Catalog Number: 25386
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9H2W1
Gene ID:64231
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 19 amino acid peptide near the amino terminus of human MS4A6A.
- other_names:
- Membrane-spanning 4-domains subfamily A member 6A, Four-span transmembrane protein 3, 4SPAN3, 4SPAN3.2, CD20 antigen-like 3, CD20L3, CDA01
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- At least three isoforms of MS4A6A are known to exist; this antibody will detect the two longer isoforms. MS4A6A antibody is predicted to not cross-react with MS4A family members.
- Background:
- The MS4A gene family in humans includes CD20 (MS4A1), FcRbeta (MS4A2), Htm4 (MS4A3), and at least 13 other genes encoding membrane proteins, most having characteristic tetraspanning topology and similar intron/exon splice boundaries. All family members display unique expression patterns among hematopoietic cells and non-lymphoid tissues. The function of MS4A6A has been suggested to be involved in signal transduction as a component of a multimeric receptor complex in Alzheimer’s disease and cancer.
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