Product Datasheet
ARHGAP39 Antibody
Catalog Number: 25342
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9C0H5
Gene ID:80728
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against an 18 amino acid peptide near the carboxy terminus of human ARHGAP39.
- other_names:
- Rho GTPase activating protein 39, CrGAP, CrossGAP, Vilse
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- ARHGAP39 antibody is predicted to not cross-react with other RhoGAP protein family members.
- Background:
- Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.
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