Product Datasheet  
LY6K Antibody  
Catalog Number: 25338  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q17RY6
    Gene ID:54742
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against an 18 amino acid peptide near the amino terminus of human LY6K.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Lymphocyte antigen 6 complex locus K, ly-6K, CT97
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • Multiple isoforms of LY6K are known to exist.
  • Applications：  
  • ELISA WB
  • Background：  
  • The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.



 
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