Product Datasheet
TMEM204 Antibody
Catalog Number: 25334
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9BSN7
Gene ID:79652
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 17 amino acid peptide near the carboxy terminus of human TMEM204.
- other_names:
- Transmembrane protein 204, Claudin-like protein 24, CLP24
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.
- Background:
- Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.
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