Product Datasheet  
SYTL5 Antibody  
Catalog Number: 25333  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8TDW5
    Gene ID:94122
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 17 amino acid peptide near the amino terminus of human SYTL5.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • SLP5, Synaptotagmin-like protein 5
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.



 
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