Product Datasheet  
TMEM88 Antibody  
Catalog Number: 25326  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q6PEY1
    Gene ID:92162
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 19 amino acid peptide near the carboxy terminus of human TMEM88.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Transmembrane protein 88
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • At least two isoforms of TMEM88 are known to exist; this antibody will recognize both isoforms.
  • Applications：  
  • ELISA WB
  • Background：  
  • Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.



 
© Signalway Biotechnology All Rights Reserved.