Product Datasheet  
ZNF346(CT) Antibody  
Catalog Number: 25268  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9UL40
    Gene ID:23567
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 20 amino acid peptide near the carboxy terminus of human ZNF346.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • other_names:  
  • Zinc finger protein 346, Just another zinc finger protein, JAZ
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist; this antibody will recognize the two longest isoforms
  • Applications:  
  • ELISA WB
  • Background:  
  • ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.



 
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