Product Datasheet  
ZIP12 Antibody  
Catalog Number: 25234  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q504Y0
    Gene ID:221074
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 15 amino acid peptide near the amino terminus of human ZIP12.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • Solute carrier family 39 member A12, Slc39A12, LZT-Hs8
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • At least four isoforms of ZIP12 are known to exist. ZIP12 antibody is predicted to not cross-react with other ZIP family members.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.



 
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