Product Datasheet  
ZIP6 Antibody  
Catalog Number: 25229  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q13433
    Gene ID:25800
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 16 amino acid peptide near the center of human ZIP6.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • other_names:  
  • Solute carrier family 39 member A6, Slc39A6, LIV-1
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Applications:  
  • ELISA WB IHC
  • Background:  
  • The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.



 
© Signalway Biotechnology All Rights Reserved.