Product Datasheet
ZIP5 Antibody
Catalog Number: 25228
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q6ZMH5
Gene ID:283375
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 17 amino acid peptide near the center of human ZIP5.
- other_names:
- Solute carrier family 39 member A5, Slc39A5, LZT-Hs1
- Purification:
- Affinity chromatography purified via peptide column
- Applications:
- ELISA WB IHC
- Background:
- The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
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