Product Datasheet
USP10 Antibody
Catalog Number: 25134
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q14694
Gene ID:9100
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 16 amino acid peptide near the amino terminus of human USP10.
- other_names:
- Ubiquitin specific peptidase 10, ubiquitin carboxyl-terminal hydrolase 10, UBPO, de-ubiquitinating enzyme 10
- Purification:
- Affinity chromatography purified via peptide column
- Applications:
- ELISA WB ICC
- Background:
- USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.
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