Product Datasheet
PLEKHM2 Antibody
Catalog Number: 25004
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8IWE5
Gene ID:23207
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 17 amino acid peptide from near the carboxy terminus of human PLEKHM2.
- other_names:
- Pleckstrin homology domain containing family M member 2, SKIP
- Purification:
- Affinity chromatography purified via peptide column
- Applications:
- ELISA WB IHC
- Background:
- PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
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