Product Datasheet
AGTR2 Antibody
Catalog Number: 24967
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P50052
Gene ID:186
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 16 amino acid peptide from near the center of human AGTR2.
- other_names:
- Angiotensin II receptor type 2, AT2, AT2R, MRX88
- Purification:
- Affinity chromatography purified via peptide column
- Applications:
- ELISA WB IHC
- Background:
- Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
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