Product Datasheet
Swine H1N1 Nonstructural Protein 1 Antibody
Catalog Number: 24953
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:C3W5S7
Gene ID:
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a synthetic peptide from. The swine-Origin Influenza NS1.
- other_names:
- Swine-Origin Influenza A (H1N1) Nonstructural Protein 1, NS1, S-OIV NS1
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- This antibody is specific for the Swine-Origin H1N1 influenza NS1 and will not recognize the corresponding NS1 sequence from the seasonal H1N1 influenza (A/South Australia/51/2005 (H1N1)).
- Background:
- Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2�?5�?OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
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